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| Creatine Kinase - NAC, 10 x 6 ml | |
| Product | Creatine Kinase - NAC, 10 x 6 ml |
|---|---|
| Catalog Number | BQ 014A-CR |
| Quantity | 60 Tests |
| Sample Type | Serum |
| Description | For the quantitative determination of Creatine Kinase in human serum. Creatine Kinase (CK) plays an important role in the energy-storing mechanism of tissue by catalyzing the reversible reaction between creatine and ATP to form creatine phosphate and ADP. CK is distributed in various organs; the highest activities (in decreasing order) are skeletal muscle, heart, and brain. Thus, determination of CK is an aid in diagnosing muscular dystrophy and other diseases of the skeletal muscles, myocardial infarction, hypothyroidism, renal diseases, and/or dysfunction. CK catalyzes the conversion of creatine phosphate and ADP to creatine and ATP. The ATP and glucose are converted to ADP and glucose-6-phosphate by hexokinase (HK). Glucose-6-phosphate dehydrogenase (G-6-PDH) oxidizes at the D-glucose-6-phosphate and reduces the nicotinamide adenine dinucleotide (NAD). The rate of NADH formation, measured at 340nm, is directly proportional to serum CK activity. |
| Species | Human |